Cytogenetics, Chromosome 11, Mixed-Lineage Leukemia (MLL)

Today, Dr. Lewis talked to us about my mom's cytogenetics results.  I will try to describe this in a accurate way, but please keep in mind that my road to learning the language of Cancer is still relatively new.  I also need to brush up on some high school and college biology classes!She has abnormalities in Chromosome 11. The results say:Abnormal female karyotype with a deletion in the q-arm* of chromosome 11 in 4/5 metaphase cells available analyzed.  These abnormal cells also had additional non-clonal abnormalities.The remaining 1/5 cell showed a 46,XX karyotype.Submission of a follow-up specimen to monitor karyotypic evolution should be considered as clinically indicated.  Karyotypic evolution often precedes disease progression. *I read that q-arm = long-armThis basically means that she is high risk.  The abnormalities of Chromosome 11 affects the Mixed Lineage Leukemia (MLL) gene.  The possibility of a stem-cell transplant is quite high at the moment.  There is much to learn about cytogenetics and I will be updating this post as I learn more.I found this article about Chromosome 11 and MLL.